rheumatology-congress-physiology-2019-posters-abstracts

Page 44

December 9-10, 2019 | Barcelona, Spain

Volume 14

ARTHRITIS AND RHEUMATOLOGY

ANATOMY AND PHYSIOLOGY

International Conference on

Journal of Orthopaedics Trauma Surgery

and Related Research

Rheumatology Congress 2019 & Anatomy and Physiology 2019

December 09-10, 2019

J Orthop Trauma Surg Rel Res, ISSN: 1897-2276

Response to immunomodulator treatment as diagnostic criterion of cirrhosis due to

autoimmune hepatitis

Laura Camila Cáceres

Universidad Autónoma de Bucaramanga, Colombia

utoimmune hepatitis is a progressive inflammatory disease that directly attacks the hepatocytes, in the long term and without

timely treatment leads to cirrhosis. Worldwide, it is estimated between 11.6-35.9 cases/100,000 inhabitants, therefore, in

medical practice it is low considered in the diagnosis of chronic hepatitis; because the simplified diagnostic criteria for this disease

are complex, since they focus on expensive diagnostic means and in low and middle income countries, access is difficult, the

opportunity for diagnosis and treatment is also important Consider the sensitivity of these. In addition, it is important to consider

the sensitivity of these diagnostic means. Some cases are atypical, in which clinical improvement with immunomodulatory

treatment is highlighted as a diagnostic criterion of the classic criteria of 1999 to establish the diagnosis of autoimmune hepatitis

due to the high sensitivity of the response to treatment evidenced at 48 hours. Therefore, it is important to consider the start of

immunomodulatory treatment against autoimmune hepatitis once the main causes of chronic liver disease have been ruled out,

despite not fulfilling the diagnostic criteria, as this prevented progression of the disease, a fatal outcome and mortality in the

patient. The absence of immunosuppressive therapy between diagnostic criteria is a limitation for diagnosis and treatment.