orthopedics-2019-scientifictracks

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November 13-14, 2019 | London, UK

ORTHOPEDICS, OSTEOPOROSIS & TRAUMA

International Conference on

Journal of Orthopaedics Trauma Surgery and

Related Research

Orthopedics 2019

November 13-14, 2019

J Orthop Trauma Surg Rel Res, Volume 14

Volume: 14 | ISSN: 1897-2276

Predictors of meniscal allograft transplantation outcome: A systematic review

Daniele Fanelli

Aberdeen Royal Infirmary, UK

his systematic review investigates factors associated with outcomes after Meniscal Allograft Transplantation (MAT). The

PubMed, Scopus and Cochrane Central Register databases were used to search relevant articles in April 2018. Studies that

evaluated at least 1 association between a factor and outcomes were extracted. Of 3381 titles, 52 studies were finally analyzed.

Data about predictors, Patient Reported Outcome scores (PROMs) and failure rates were extracted for quantitative and qualitative

analysis. A total of 3382 patients and 3460 transplants were identified. Thirty different predictors were reported in the current

MAT literature, 18 of which by at least 2 studies. Subgroup analysis showed that lateral MAT had higher postoperative values

than medial MAT in Lysholm (p=0.0102) and IKDC (p=0.0056) scores. Soft tissue fixation showed higher postoperative IKDC

scores than bone fixation (p=0.0008). Fresh frozen allografts had higher Lysholm scores (p<0.0001) and showed significantly

lower failure rates (p<0.0001) than cryopreserved allografts. Age (p<0.015, β=0.80), sex (p<0.034, β=-8.52) and BMI (p< 0.014,

β=-4.87) demonstrated an association with PROMs in the regression model. Qualitative analysis found moderate evidence that

a higher number of previous procedures in the same knee is an independent predictor of transplant failure. Conflicting evidence

was found with regard to chondral damage, time from meniscectomy, smoke, sport level, worker's compensation status and

preoperative Lysholm score as predictors of outcomes. Our review suggests that the ideal candidate to undergo MAT is a young

male of normal weight with no previous knee surgeries, treated with a lateral isolated procedure.

Biography

Daniele Fanelli is currently a Foundation Year 1 doctor at Aberdeen Royal Infirmary with a strong interest in Orthopaedic research. He

has worked as a research collaborator for the Trauma and Orthopaedics department of the Magna Graecia University, Catanzaro, Italy.

His research work has mainly focused on the area of foot and ankle surgery and meniscal transplantation. He is also a postgraduate

student at the University of Glasgow, undertaking a MSc in Health-Professions Education.