

Page 24
Arthroplasty 2019
June 24-25, 2019
Volume 14
Journal of Orthopaedics Trauma Surgery and Related Research
Arthroplasty
June 24-25, 2019 | Rome, Italy
12
th
International Conference on
Incidence and risk factors of acute kidney injury after total joint arthroplasty: A
retrospective cohort study
Izziddine Vial
University of Manchester, UK
Background:
Acute Kidney Injury (AKI) is a common complication post-arthroplasty, although it has not been extensively
studied. We carried out a retrospective study to determine the incidence and risk factors of AKI in patients undergoing
total joint arthroplasty (TJA).
Aims:
Calculate the incidence of patients suffering from AKI after the changes made from the 2014 audit. Find out the
major pre- and perioperative risk factors of AKI in the cohort of patients.
Method:
We reviewed the medical records of all patients who underwent elective TJA from December 2014 to January
2017 at the Salford Royal Hospital, UK. AKI was defined using the AKIN, RIFLE and KDIGO criteria in patients with
worsened renal function post-arthroplasty. We analysed the association of the demographics, risk factors, medications
and use of peri-operative IV fluids with AKI. A logistic regression was performed to find any correlation between these
factors and incidence of AKI.
Results:
197 patients were included in our study, the mean age was 70.2 and male to female ratio was 6:5. Of these,
32(16.2%) developed an AKI. The multivariate logistic regression revealed 4 independent factors associated with the risk
of AKI; age (P =0.0011, OR 1.07, 95% CI 1.03-1.18), obesity (P =0.003, OR 6.4, 95% CI 2.34-17.5), smoking (P =0.0482,
OR 3.76, 95% CI 1.01-14.0) and COPD (P =0.0253, OR 3.85, 95% CI 1.18-12.5).
Conclusion:
The incidence of AKI post-arthroplasty was found to be much higher than stated in other literatures. The
recognition of the high incidence and multiple independent risk factors will allow a better approach to peri-operative
management, limiting the risks of AKI. Our study also highlighted the importance of documenting urine output and the
need to repeat the renal function test 3 months after an AKI to assess recovery.
Biography
Izziddine Vial is an intercalating medical student at Hull York Medical School doing MSc in Clinical anatomy. He will continue his medical
studies at the University of Manchester as a 4th-year medical student. He has a special interest in trauma and orthopaedics.
izziddine.vial@student.manchester.ac.ukIzziddine Vial, J.Orthop.Trauma Surg.Relat.Res. | Volume 14
ISSN:2449-9145