An Official Journal of Polish Society of Orthopaedics and Traumatology
ISSN:1897-2276
e-ISSN: 2449-9145
Editorial Office, Orthopaedics Trauma Surgery and Related Research, Poland
Short commentary
Painful intervertebral disc degeneration
Author(s):
Olivia Gray*
Low Back Pain (LBP) is a common musculoskeletal illness that causes significant social and economic consequences. It is the main cause of disability. Inflammation and associated signaling pathways have recently been recognized as critical roles in the start and progression of disc degeneration, a major contributor to LBP. Inflammatory mediators are also important in the development of discogenic LBP. LBP suppression is a main goal of therapeutic management, but disc research studies haven't paid enough attention to it. A discussion of the function of inflammation in IVD degeneration and pain induction is included in this summary of advancements in inflammation-related pain in disc degeneration. Puncture models, mechanical models, and spontaneous models are presented as the principal animal models for studying painful disc degeneration, as well as the underlying signaling pathways. Fur.. Read More»
10.37532/1897-2276.2021.16(1).49
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